协和医学杂志

2011, v.2(01) 28-32

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活动期感染性心内膜炎手术治疗的近远期疗效
Short-and Long-term Outcomes of Surgical Treatment of Active Infective Endocarditis

刘剑州;苗齐;刘兴荣;张恒;张超纪;马国涛;曹丽华;王超;李晓凤;邓海波;陈广俊;刘薇;黄宇光;石岩;王晓亭;刘大为;周宝桐;王焕玲;
LIU Jian-zhou1,MIAO Qi1,LIU Xing-rong1,ZHANG Heng1,ZHANG Chao-ji1,MA Guo-tao1,CAO Li-hua1,WANG Chao1,LI Xiao-feng1,DENG Hai-bo1,CHEN Guang-jun2,LIU Wei2,HUANG Yu-guang2,SHI Yan3,WANG Xiao-ting3,LIU Da-wei3,ZHOU Bao-tong4,WANG Huan-ling41Department of Cardiac Surgery,2Department of Anesthesiology,3Intensive Care Unit,4Department of infectious Disease,Peking Union Medical College Hospital,Chinese Academy of Medical Science & Peking Union Medical College,Beijing 100730,China

摘要(Abstract):

目的回顾性分析北京协和医院71例活动期感染性心内膜炎(active infective endocarditis,AIE)患者手术治疗的近远期疗效。方法 2001年1月至2010年7月,根据杜克诊断标准(Duke criteria)共确诊感染性心内膜炎(infective endocarditis,IE)209例,78例接受了手术治疗,选择其中71例活动期感染性心内膜炎患者的临床资料,进行回顾性分析;排除病例包括同期人工瓣膜感染性心内膜炎和愈合期心内膜炎。结果 71例活动期感染性心内膜炎患者的平均年龄为(44.6±14.4)岁,其中男性55例(77.5%)。链球菌是最常见的致病菌。术后住院期间死亡2例(2.8%)。平均随访时间(42.4±32.4)个月(1~126个月),1、5和10年实际生存率分别为(98.5±1.5)%、(92.6±4.5)%和(79.4±12.8)%。结论手术治疗活动期感染性心内膜炎的近远期临床疗效满意。
Objective To analyze the short-and long-term outcomes of surgical treatment of active infective endocarditis(IE).Methods Surgeries were performed for 71 patients with active IE from January 2001 to July 2010.Patients with prosthetic valve or healed IE were excluded.Results Of these 71 patients,the mean age was 44.6±14.4 years,and 55(77.5%)were men.Streptococcus was the most common causative microorganism.Two patients(2.8%)died during post-surgical hospital stay.Survivors were followed up for 42.4±32.4 months.The actuarial 1-,5-,and 10-year survival rates were(98.5±1.5)%,(92.6±4.5)%,and(79.4±12.8)%,respectively.Conclusion Surgery can achieve satisfactory short-and long-term effectiveness for active IE.

关键词(KeyWords): 活动期感染性心内膜炎;手术治疗
active infective endocarditis;surgery

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作者(Author): 刘剑州;苗齐;刘兴荣;张恒;张超纪;马国涛;曹丽华;王超;李晓凤;邓海波;陈广俊;刘薇;黄宇光;石岩;王晓亭;刘大为;周宝桐;王焕玲;
LIU Jian-zhou1,MIAO Qi1,LIU Xing-rong1,ZHANG Heng1,ZHANG Chao-ji1,MA Guo-tao1,CAO Li-hua1,WANG Chao1,LI Xiao-feng1,DENG Hai-bo1,CHEN Guang-jun2,LIU Wei2,HUANG Yu-guang2,SHI Yan3,WANG Xiao-ting3,LIU Da-wei3,ZHOU Bao-tong4,WANG Huan-ling41Department of Cardiac Surgery,2Department of Anesthesiology,3Intensive Care Unit,4Department of infectious Disease,Peking Union Medical College Hospital,Chinese Academy of Medical Science & Peking Union Medical College,Beijing 100730,China

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