协和医学杂志

2018, v.9(01) 69-74

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肌萎缩侧索硬化的临床分型、分期及病情评估
Clinical Phenotype Classification,Staging and Prognostic Evaluation of Amyotrophic Lateral Sclerosis

李晓光;刘明生;崔丽英;
LI Xiao-guang;LIU Ming-sheng;CUI Li-ying;Department of Neurology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

摘要(Abstract):

肌萎缩侧索硬化(amyotrophic lateral sclerosis,ALS)是一种进展性神经系统变性疾病。其起病隐袭,进展缓慢,因呼吸衰竭死亡,目前尚无治愈方法。近年来研究表明多种措施可延长患者存活期,提高患者生活质量。为了科学合理地治疗ALS,本文就其临床分型、分期、治疗模式及对ALS病情进展的评估和随访方法进行介绍。
Amyotrophic lateral sclerosis(ALS) is a progressive neurodegenerative disease,characterized by insidious onset,slow progression,and death due to respiratory failure. There is no cure for it. Recent studies show that many measures can prolong the survival of patients with ALS,and improve their quality of life. In order to treat ALS scientifically and rationally,this paper introduces its clinical classification,staging,treatment mode,and methods for evaluating and following up the progress of ALS disease.

关键词(KeyWords): 肌萎缩侧索硬化;分型;分期;病情评估
amyotrophic lateral sclerosis;phenotype classification;staging;disease outcome evaluation

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作者(Author): 李晓光;刘明生;崔丽英;
LI Xiao-guang;LIU Ming-sheng;CUI Li-ying;Department of Neurology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College;

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